megatomi.com - An Overview
Our new Very clear+ tissue clearing system is the only method that delipidates samples without having adjust in morphology and with nominal impact on structural integrity.Megatome is a vibrating microtome meant to part a broad selection of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With high blade vibrating frequency and minimized blade deflection, Megatome allows higher-throughput tissue sectioning with uniform area profile, together with nominal tissue damage and information reduction.
Antibodies may possibly take weeks to diffuse by only a few millimeters of tissue, by using a steep labeling gradient from surface to Main.
Megatome is designed for accuracy: the blade vibrates at the next frequency and larger amplitude vary than other microtomes, and includes a exceptional deflection Regulate mechanism.
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Our preformulated EasyIndex Option raises and homogenize the refractive index of delipidated tissue samples, rendering them absolutely transparent. This enables gentle penetration into the sample and ensures the acquisition of higher-resolution, in-target picture knowledge.
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eFLASH is usually a swift tissue labeling strategy that permits for uniform complete-organ staining in megatomi.com 20 rounds of labeling.
The SmartSPIM light sheet microscope delivers unparalleled resolution and acquisition pace throughout intact tissue volumes, when its modular design and style enables you to enhance and personalize person components.
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Our novel SHIELD tissue preservation approach kinds intramolecular bonds employing polyfunctional, versatile epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.